OUR SCIENCE

Engineering high-affinity macrocyclic peptides via trackable, real-time ranking of billions of biomolecular variants

ARZANYA

Publications and news

2026 · PUBLICATION

Yeast display technology enables rapid discovery of low-nanomolar macrocyclic peptide inhibitors of human angiotensin-converting enzyme 2

2026 · PUBLICATION

An affordable and low-waste protocol for rapid and robust solid-phase peptide synthesis at elevated temperatures

2025 · PUBLICATION

Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking

2025 · PUBLICATION

Quantitative Affinity Screening of Macrocyclic Peptide Libraries Using Yeast Surface Display Technology

2024 · NEWS

Ca’ Foscari University News – Many thanks to Ca’ Foscari University of Venice for featuring our technology and mission in their latest article: ‘Yeast-encoded biomolecules for innovative drugs’.

2024 · NEWS

Luciano Miotto Award for Female Startups – Arzanya wins the Special Luciano Miotto Award for Female Startups. This award recognizes excellence in female entrepreneurship and is presented to young businesses where women represent at least 60% of the core team. Congratulations to the whole team for this well-deserved recognition!

2023 · NEWS

BCC Innovation Festival – One of Arzanya’s core objectives is to create fair, inclusive, and local employment. Our commitment to these values led Arzanya to win the BCC Innovation Festival, an award that recognizes innovation and the pursuit of the UN 2030 Agenda goals promoted by the Iccrea Banking Group.

Precision Discovery

Quantitative Macrocyclic Peptide Discovery and Engineering: Precision at Scale

Massive Throughput

Our proprietary platform is designed to accelerate the discovery of genetically encoded macrocyclic peptides with high affinity and selectivity against challenging therapeutic targets.

Synthesis-Free

We integrate yeast surface display with quantitative flow cytometry to analyze billions of macrocyclic peptide variants in parallel. This approach is rapid, fully trackable, and eliminates the need for upfront chemical synthesis.

Real-time Ranking

Unlike traditional methods, our technology enables real-time monitoring and ranking of binding affinities, providing full control over the selection process and delivering high-quality results faster (’failing early to succeed faster’)